Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
- Creator: Keaton, Jacob M. , Kamali, Zoha , Young, William J. , Lehtimäki, T , Raitakari, OT , Johnson, AD , Newton-Cheh, C , Brown, MJ , Dominiczak, AF , Sever, PJ , Poulter, N , Chambers, JC , Elosua, R , Traylor, Matthew , Siscovick, D , Esko, T , Metspalu, A , Strawbridge, RJ , Laakso, M , Hamsten, A , Hottenga, J-J , de Geus, E , Morris, AD , Palmer, CNA , Giri, Ayush , Nolte, IM , Milaneschi, Y , Marten, J , Wright, A , Zeggini, E , Howson, JMM , O'Donnell, CJ , Spector, T , Nalls, MA , Simonsick, EM , Zheng, Zhili , Liu, Y , van Duijn, CM , Butterworth, AS , Danesh, JN , Menni, C , Wareham, NJ , Khaw, K-T , Sun, YV , Wilson, PWF , Cho, K , Zeng, Jian , Visscher, PM , Denny, JC , Million Veteran Program, , Lifelines Cohort Study, , CHARGE consortium, , ICBP Consortium, , Levy, D , Edwards, TL , Munroe, PB , Snieder, H , Chasman, Daniel I. , Warren, HR , Morris, Andrew P. , Caulfield, Mark J. , Hwang, Shih-Jen , Kooner, Jaspal S. , Xie, Tian , Attia, John R. , Attia, JR , Morrison, AC , Loos, RJF , Kristiansson, K , Schmidt, R , Hicks, AA , Pramstaller, PP , Nelson, CP , Samani, NJ , Vaez, Ahmad , Risch, L , Gyllensten, U , Melander, O , Riese, H , Wilson, JF , Campbell, H , Rich, SS , Psaty, BM , Lu, Y , Rotter, JI , Williams, Ariel , Guo, X , Rice, KM , Vollenweider, P , Sundström, J , Langenberg, C , Tobin, MD , Giedraitis, V , Luan, J , Tuomilehto, J , Kutalik, Z , Goleva, Slavina B. , Ripatti, S , Salomaa, V , Girotto, G , Trompet, S , Jukema, JW , van der Harst, P , Ridker, PM , Giulianini, F , Vitart, V , Goel, A , Ani, Alireza , Watkins, H , Harris, SE , Deary, IJ , van der Most, PJ , Oldehinkel, AJ , Keavney, BD , Hayward, C , Campbell, A , Boehnke, M , Scott, LJ , Evangelou, Evangelos , Boutin, T , Mamasoula, C , Järvelin, M-R , Peters, A , Gieger, C , Lakatta, EG , Cucca, F , Hui, J , Knekt, P , Enroth, S , Hellwege, Jacklyn N. , De Borst, MH , Polašek, O , Concas, MP , Catamo, E , Cocca, M , Li-Gao, R , Hofer, E , Schmidt, H , Spedicati, B , Waldenberger, M , Yengo, Loic , Strachan, DP , Laan, M , Teumer, A , Dörr, M , Gudnason, V , Cook, JP , Ruggiero, D , Kolcic, I , Boerwinkle, E , Traglia, M
- Resource Type: journal article
- Date: 2024
Genetic effects on the timing of parturition and links to fetal birth weight
- Creator: Solé-Navais, Pol , Flatley, Christopher , Brumpton, Ben , Skotte, Line , Borges, Maria C. , Helgeland, Øyvind , Mahajan, Anubha , Wielscher, Matthias , Lin, Frederick , Briggs, Catherine , Wang, Carol A. , Moen, Gunn-Helen , Steinthorsdottir, Valgerdur , Beaumont, Robin N. , Bradfield, JP , Abraham, A , Thorleifsson, G , Gabrielsen, ME , Ostrowski, SR , Modzelewska, D , Nohr, EA , Hypponen, E , Srivastava, A , Vaudel, Marc , Talbot, O , Allard, C , Williams, SM , Menon, R , Shields, BM , Sveinbjornsson, G , Xu, H , Melbye, M , Lowe, W , Bouchard, L , Juodakis, Julius , Oken, E , Pedersen, OB , Gudbjartsson, DF , Erikstrup, C , Sørensen, E , Early Growth Genetics Consortium, , Estonian Biobank Research Team, , Danish Blood Donor Study Genomic Consortium, , Lie, RT , Teramo, K , Chen, Jing , Hallman, M , Juliusdottir, T , Hakonarson, H , Ullum, H , Hattersley, AT , Sletner, L , Merialdi, M , Rifas-Shiman, SL , Steingrimsdottir, T , Scholtens, D , Laisk, Triin , Power, C , West, J , Nyegaard, M , Capra, JA , Skogholt, AH , Magnus, P , Andreassen, OA , Thorsteinsdottir, U , Grant, SFA , Qvigstad, E , LaBella, Abigail L. , Pennell, Craig E. , Hivert, M-F , Hayes, GM , Jarvelin, M-R , McCarthy, MI , Lawlor, DA , Nielsen, HS , Mägi, R , Rokas, A , Hveem, K , Westergaard, David , Stefansson, K , Feenstra, B , Njolstad, P , Muglia, LJ , Freathy, RM , Johansson, S , Zhang, G , Jacobsson, B , Bacelis, Jonas
- Resource Type: journal article
- Date: 2023
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
- Creator: Beaumont, Robin N. , Flatley, Christopher , Albiñana, Clara , Ronkainen, Justiina , Fadista, João , Stinson, Sara Elizabeth , Trajanoska, Katerina , Wang, Carol A. , Westergaard, David , Srinivasan, Sundararajan , Sánchez-Soriano, Carlos , Bilbao, Jose Ramon , Vaudel, Marc , Pennell, Craig E. , Wu, Xiaoping , Chen, Jing , Moen, Gunn-Helen , Skotte, Line , Helgeland, Øyvind , Solé-Navais, Pol , Banasik, Karina
- Resource Type: journal article
- Date: 2023
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
- Creator: Shrine, Nick , Izquierdo, Abril G. , Hobbs, Brian D. , Foong, RE , Harris, SE , Taylor, A , Redmond, P , Cook, JP , Mahajan, A , Lind, L , Palviainen, T , Lehtimäki, T , Raitakari, OT , Moll, Matthew , Kaprio, J , Rantanen, T , Pietiläinen, KH , Cox, SR , Pennell, CE , Hall, GL , Gauderman, WJ , Brightling, C , Wilson, JF , Vasankari, T , Kim, Wonji , Laitinen, T , Salomaa, V , Mook-Kanamori, DO , Timpson, NJ , Zeggini, E , Dupuis, J , Hayward, C , Brumpton, B , Langenberg, C , Weiss, S , Tal-Singer, Ruth , Homuth, G , Schmidt, CO , Probst-Hensch, N , Jarvelin, M-R , Morrison, AC , Polasek, O , Rudan, I , Lee, J-H , Sayers, I , Rawlins, EL , Bakke, Per , Dudbridge, F , Silverman, EK , Strachan, DP , Walters, RG , Morris, AP , London, SJ , Cho, MH , Wain, LV , Hall, IP , Tobin, MD , Fawcett, Katherine A. , John, Catherine , Coley, Kayesha , Piga, Noemi Nicole , Pozarickij, Alfred , Chen, Jing , Wang, Carol A. , Pennell, Craig E. , Chen, Z , Li, L , China Kadoorie Biobank Collaborative Group, , Wijnant, SRA , Lahousse, L , Brusselle, G , Uitterlinden, AG , Manichaikul, A , Packer, Richard , Oelsner, EC , Rich, SS , Barr, RG , Kerr, SM , Vitart, V , Brown, MR , Wielscher, M , Imboden, M , Jeong, A , Bartz, TM , Hall, Robert J. , Gharib, SA , Flexeder, C , Karrasch, S , Gieger, C , Peters, A , Stubbe, B , Hu, X , Ortega, VE , Meyers, DA , Bleecker, ER , Guyatt, Anna L. , Gabriel, SB , Gupta, N , Smith, AV , Luan, J , Zhao, J-H , Hansen, AF , Langhammer, A , Willer, C , Bhatta, L , Porteous, D , Batini, Chiara , Smith, BH , Campbell, A , Sofer, T , Lee, J , Daviglus, ML , Yu, B , Lim, E , Xu, H , O'Connor, GT , Thareja, G , Thompson, Rebecca J. , Albagha, OME , Qatar Genome Program Research (QGPR) Consortium, , Suhre, K , Granell, R , Faquih, TO , Hiemstra, PS , Slats, AM , Mullin, BH , Hui, J , James, A , Pavuluri, Chandan , Beilby, J , Patasova, K , Hysi, P , Koskela, JT , Wyss, AB , Jin, J , Sikdar, S , Lee, M , May-Wilson, S , Pirastu, N , Malik, Vidhi , Kentistou, KA , Joshi, PK , Timmers, PRHJ , Williams, AT , Free, RC , Wang, X , Morrison, JL , Gilliland, FD , Wang, CA
- Resource Type: journal article
- Date: 2023
Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
- Creator: Liu, Dongjing , Meyer, Dara , Dobbyn, Amanda , Schall, Ulrich , Scott, Rodney J. , Tooney, Paul A. , Lebovitch, Dannielle , Moya, Emily , Nguyen, Tan-Hoang , Wilkins, Lillian , Hassan, Arsalan , Aghanwa, Henry S. , Ansari, Moin , Asif, Aftab , Aslam, Rubina , Fennessy, Brian , Ayuso, JL , Bigdeli, T , Bignotti, S , Bobes, J , Bradley, B , Buckley, P , Cairns, Murray J. , Catts, SV , Chaudhry, AR , Cohen, D , Feng, Claudia , Collins, BL , Consoli, A , Costas, J , Crespo-Facorro, B , Daskalakis, NP , Davidson, M , Davis, KL , Dickerson, F , Dogar, IA , Drapeau, E , Cheng, Esther , Fañanás, L , Fanous, A , Fatima, W , Fatjo, M , Filippich, C , Friedman, J , Fullard, JF , Georgakopoulos, P , Giannitelli, M , Giegling, I , Johnson, Jessica S. , Green, MJ , Guillin, O , Gutierrez, B , Handoko, HY , Hansen, SK , Haroon, M , Haroutunian, V , Henskens, Frans A. , Hussain, F , Jablensky, AV , Park, You Jeong , Junejo, J , Kelly, Brian J. , Khan, SUDA , Khan, MNS , Khan, A , Khawaja, HR , Khizar, B , Kleopoulos, SP , Knowles, J , Konte, B , Rieder, Marysia-Kolbe , Kusumawardhani, AAAA , Leghari, N , Liu, X , Lori, A , Loughland, Carmel M. , Mahmood, K , Mahmood, S , Malaspina, D , Malik, D , McNaughton, A , Ascolillo, Steven , Michie, Patricia T. , Michopolous, V , Molina, E , Molto, MD , Munir, A , Muntané, G , Naeem, F , Nancarrow, DJ , Nasar, A , Nasr, T , de Pins, Agathe , Ohaeri, JU , Ott, J , Pantelis, C , Periyasamy, S , Pinto, AG , Powers, A , Ramos, B , Rana, NH , Rapaport, M , Reichenberg, A
- Resource Type: journal article
- Date: 2023
Discovery of 42 genome-wide significant loci associated with dyslexia
- Creator: Doust, Catherine , Fontanillas, Pierre , Bell, Robert K. , Pennell, Craig E. , Bielenberg, Jessica , Bryc, Katarzyna , Bullis, Emily , Coker, Daniella , Partida, Gabriel Cuellar , Dhamija, Devika , Das, Sayantan , Elson, Sarah L. , Filshtein, Teresa , Eising, Else , Fletez-Brant, Kipper , Freyman, W , Gandhi, PM , Heilbron, K , Hicks, B , Hinds, DA , Jewett, EM , Jiang, Y , Kukar, K , Lin, KH , Gordon, Scott D. , Lowe, M , McCreight, J , McIntyre, MH , Micheletti, SJ , Moreno, ME , Mountain, JL , Nandakumar, P , Noblin, ES , O’Connell, J , Petrakovitz, AA , Wang, Zhengjun , Poznik, GD , Schumacher, M , Shastri, AJ , Shelton, JF , Shi, J , Shringarpure, S , Tran, V , Tung, JY , Wang, X , Wang, W , Alagöz, Gökberk , Weldon, CH , Wilton, P , Hernandez, A , Wong, Carol A. , Tchakouté, CT , Abbondanza, F , Allegrini, AG , Andlauer, TFM , Barr, CL , Bernard, M , Molz, Barbara , Blokland, K , Bonte, M , Boomsma, DI , Bourgeron, T , Brandeis, D , Carreiras, M , Ceroni, F , Csépe, V , Dale, PS , de Jong, PF , Aslibekyan, Stella , Démonet, JF , de Zeeuw, EL , Feng, Y , Franken, MCJ , Gerritse, M , Gialluisi, A , Guger, SL , Hayiou-Thomas, ME , Hernández-Cabrera, J , Hottenga, JJ , Auton, Adam , Hulme, C , Jansen, PR , Kere, J , Kerr, EN , Koomar, T , Landerl, K , Leonard, GT , Liao, Z , Lovett, MW , Lyytinen, H , Babalola, Elizabeth , Martinelli, A , Maurer, U , Michaelson, JJ , Mirza-Schreiber, N , Moll, K , Morgan, AT , Müller-Myhsok, B , Newbury, DF , Nöthen, MM , Paus, T
- Resource Type: journal article
- Date: 2022
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
- Creator: Okbay, Aysu , Wu, Yeda , Jiang, Yunxuan , Hicks, Barry , Tian, Chao , Hinds, David A. , Ahlskog, Rafael , Magnusson, Patrik K. E. , Oskarsson, Sven , Hayward, Caroline , Campbell, Archie , Porteous, David J. , Wang, Nancy , Holliday, Elizabeth J. , Scott, Rodney J. , Attia, John R. , Oldmeadow, Christopher , Auton, A , Bell, RK , Bryc, K , Elson, SL , Fontanillas, P , Furlotte, NA , Jayashankar, Hariharan , Hinds, DA , Huber, KE , Kleinman, A , Litterman, NK , McCreight, JC , McIntyre, MH , Mountain, JL , Northover, CAM , Pitts, SJ , Sathirapongsasuti, JF , Bennett, Michael , Sazonova, OV , Shelton, JF , Shringarpure, S , Tung, JY , Vacic, V , Wilson, CH , Fontana, MA , Pers, TH , Rietveld, CA , Chen, GB , Nehzati, Seyed Moeen , Emilsson, V , Meddens, SFW , Pickrell, JK , Thom, K , Timshel, P , de Vlaming, R , Abdellaoui, A , Ahluwalia, TS , Bacelis, J , Baumbach, C , Sidorenko, Julia , Bjornsdottir, G , Brandsma, JH , Concas, MP , Derringer, J , Galesloot, TE , Girotto, G , Gupta, R , Hall, LM , Harris, SE , Hofer, E , Kweon, Hyeokmoon , Horikoshi, M , Huffman, JE , Kaasik, K , Kalafati, IP , Karlsson, R , Lahti, J , van der Lee, SJ , de Leeuw, C , Lind, PA , Lindgren, KO , Goldman, Grant , Liu, T , Mangino, M , Marten, J , Mihailov, E , Miller, MB , van der Most, PJ , Oldmeadow, C , Payton, A , Pervjakova, N , Peyrot, WJ , Gjorgjieva, Tamara , Qian, Y , Raitakari, O , Rueedi, R , Salvi, E , Schmidt, B , Schraut, KE , Shi, J , Smith, AV , Poot, RA , Pourcain, BS
- Resource Type: journal article
- Date: 2022
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
- Creator: Liu, Ilon , Jiang, Li , Mire, Hafsa M. , Madlener, Sibylle , Mayr, Lisa , Quezada, Michael A. , Trissal, Maria , Panditharatna, Eshini , Ernst, Kati J. , Vogelzang, Jayne , Gatesman, Taylor A. , Halbert, Matthew E. , Samuelsson, Erik R. , Palova, Hana , Pokorna, P , Sterba, J , Slaby, O , Geyeregger, R , Diaz, A , Findlay, Izac J. , Dun, Matthew D. , Resnick, A , Suvà, ML , Marco Salas, Sergio , Jones, DTW , Agnihotri, S , Svedlund, J , Koschmann, C , Haberler, C , Czech, T , Slavc, I , Cotter, JA , Ligon, KL , Alexandrescu, S , Beck, Alexander , Yung, WKA , Arrillaga-Romany, I , Gojo, J , Monje, M , Nilsson, M , Filbin, MG , Hack, Olivia A. , Jeong, Daeun , Shaw, McKenzie L. , Englinger, Bernhard , LaBelle, Jenna
- Resource Type: journal article
- Date: 2022
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
- Creator: Mullins, Niamh , Forstner, Andeas J. , Charney, Alexander W. , Kamatani, Y , Kennedy, JL , Kittel-Schneider, S , Knowles, JA , Kogevinas, M , Koromina, M , Kranz, TM , Kranzler, HR , Kubo, M , Kupka, R , Drange, Ole Kristian , Kushner, SA , Lavebratt, C , Lawrence, J , Leber, M , Lee, H-J , Lee, PH , Levy, SE , Lewis, C , Liao, C , Lucae, S , Gandal, Michael J. , Lundberg, M , MacIntyre, DJ , Maier, W , Maihofer, A , Malaspina, D , Maratou, E , Martinsson, L , Mattheisen, M , McCarroll, SA , McGregor, NW , Hagenaars, Saskia P. , McGuffin, P , McKay, JD , Medeiros, H , Medland, SE , Millischer, V , Montgomery, GW , Moran, JL , Morris, DW , Muhleisen, TW , O'Brien, N , Ikeda, Masashi , O'Donovan, C , Loohuis, LMO , Oruc, L , Papiol, S , Pardinas, AF , Perry, A , Pfennig, A , Porichi, E , Potash, JB , Quested, D , Kamitaki, Nolan , Raj, T , Rapaport, MH , DePaulo, JR , Regeer, EJ , Rice, JP , Rivas, F , Rivera, M , Roth, J , Roussos, P , Ruderfer, DM , Kim, Minsoo , Sanchez-Mora, C , Schulte, EC , Senner, F , Sharp, S , Shilling, PD , Sigurdsson, E , Sirignano, L , Slaney, C , Smeland, OB , Sobell, JL , Krebs, Kristi , Hansen, CS , Artigas, MS , Spijker, AT , Stein, DJ , Strauss, JS , Swiatkowska, B , Terao, C , Thorgeirsson, TE , Toma, C , Tooney, Paul , Panagiotaropoulou, Georgia , Tsermpini, E-E , Vawter, MP , Vedder, H , Walters, JTR , Witt, SH , Xi, S , Xu, W , Yang, JMK , Young, AH , Young, H , Schilder, Brian M. , Zandi, PP , Zhou, H , Zillich, L , Adolfsson, R , Agartz, I , Alda, M , Alfredsson, L , Babadjanova, G , Backlund, L , Baune, BT , O'Connell, Kevin S. , Sloofman, Laura G. , Bellivier, F , Bengesser, S , Berrettini, WH , Blackwood, DHR , Boehnke, M , Borglum, AD , Breen, G , Carr, VJ , Catts, S , Corvin, A , Steinberg, S , Craddock, N , Dannlowski, U , Dikeos, D , Esko, T , Etain, B , Ferentinos, P , Frye, M , Fullerton, JM , Gawlik, M , Gershon, ES , Trubetskoy, V , Goes, F , Green, MJ , Grigoroiu-Serbanescu, M , Hauser, J , Henskens, F , Hillert, J , Hong, KS , Hougaard, DM , Hultman, CM , Hveem, K , Winsvold, BS , Iwata, N , Jablensky, A , Jones, I , Jones, LA , Kahn, RS , Kelsoe, JR , Kirov, G , Landen, M , Leboyer, M , Lewis, CM , Won, H-H , Li, QS , Lissowska, J , Lochner, C , Loughland, Carmel , Martin, NG , Mathews, CA , Mayoral, F , McElroy, SL , McIntosh, AM , McMahon, FJ , Abramova, L , Melle, I , Michie, P , Milani, L , Mitchell, PB , Morken, G , Mors, O , Mortensen, PB , Mowry, B , Muller-Myhsok, B , Myers, RM , Adorjan, K , Neale, BM , Nievergelt, CM , Nordentoft, M , Nothen, MM , ODonovan, MC , Oedegaard, KJ , Olsson, T , Owen, MJ , Paciga, SA , Pantelis, C , Agerbo, E , Pato, C , Pato, MT , Patrinos, GP , Perlis, RH , Posthuma, D , Ramos-Quiroga, JA , Reif, A , Reininghaus, EZ , Ribases, M , Rietschel, M , Al Eissa, M , Ripke, S , Rouleau, GA , Saito, T , Schall, U , Schalling, M , Schofield, PR , Schulze, TG , Scott, LJ , Scott, RJ , Serretti, A , Albani, D , Weickert, CS , Smoller, JW , Stefansson, H , Stefansson, K , Stordal, E , Streit, F , Sullivan, PF , Turecki, G , Vaaler, AE , Vieta, E , Coombes, Brandon , Alliey-Rodriguez, N , Vincent, JB , Waldman, ID , Weickert, TW , Werge, T , Wray, NR , Zwart, J , Biernacka, JM , Nurnberger, J , Cichon, S , Edenberg, HJ , Anjorin, A , Stahl, EA , McQuillin, A , Di Florio, A , Ophoff, RA , Andreassen, OA , Antilla, V , Antoniou, A , Awasthi, S , Baek, JH , Baekvad-Hansen, M , Bass, N , Bauer, M , Beins, EC , Coleman, Jonathan R. I. , Bergen, SE , Birner, A , Pedersen, CB , Boen, E , Boks, MP , Bosch, R , Brum, M , Brumpton, BM , Brunkhorst-Kanaan, N , Budde, M , Qiao, Zhen , Bybjerg-Grauholm, J , Byerley, W , Cairns, Murray , Casas, M , Cervantes, P , Clarke, T-K , Cruceanu, C , Cuellar-Barboza, A , Cunningham, J , Curtis, D , Als, Thomas D. , Czerski, PM , Dale, AM , Dalkner, N , David, FS , Degenhardt, F , Djurovic, S , Dobbyn, AL , Douzenis, A , Elvsashagen, T , Escott-Price, V , Bigdeli, Tim B. , Ferrier, IN , Fiorentino, A , Foroud, TM , Forty, L , Frank, J , Frei, O , Freimer, NB , Frisen, L , Gade, K , Garnham, J , Børte, Sigrid , Gelernter, J , Pedersen, MG , Gizer, IR , Gordon, SD , Gordon-Smith, K , Greenwood, TA , Grove, J , Guzman-Parra, J , Ha, K , Haraldsson, M , Bryois, Julien , Hautzinger, M , Heilbronner, U , Hellgren, D , Herms, S , Hoffmann, P , Holmans, PA , Huckins, L , Jamain, S , Johnson, JS , Kalman, JL
- Resource Type: journal article
- Date: 2021
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
- Creator: Min, Josine L. , Hemani, Gibran , Bretherick, Andrew D. , Pennell, Craig E. , Richardson, Tom G. , Klughammer, Johanna , Iotchkova, Valentina , Sharp, Gemma , Al Khleifat, Ahmad , Shatunov, Aleksey , Iacoangeli, Alfredo , McArdle, Wendy L. , Ho, Karen M. , Hannon, Ellis , Kumar, Ashish , Söderhäll, C , Soriano-Tárraga, C , Giralt-Steinhauer, E , Kazmi, N , Mason, D , McRae, AF , Corcoran, DL , Sugden, K , Kasela, S , Dekkers, Koen F. , Cardona, A , Day, FR , Cugliari, G , Viberti, C , Guarrera, S , Lerro, M , Gupta, R , Bollepalli, S , Mandaviya, P , Zeng, Y , Castillo-Fernandez, Juan , Clarke, TK , Walker, RM , Schmoll, V , Czamara, D , Ruiz-Arenas, C , Rezwan, FI , Marioni, RE , Lin, T , Awaloff, Y , Germain, M , Luijk, Rene , Aïssi, D , Zwamborn, R , van Eijk, K , Dekker, A , van Dongen, J , Hottenga, JJ , Willemsen, G , Xu, CJ , Barturen, G , Català-Moll, F , Carnero-Montoro, Elena , Kerick, M , Wang, Carol , Melton, P , Elliott, HR , Shin, J , Bernard, M , Yet, I , Smart, M , Gorrie-Stone, T , Shaw, C , Lawson, Daniel J. , Al Chalabi, A , Ring, SM , Pershagen, G , Melén, E , Jiménez-Conde, J , Roquer, J , Lawlor, DA , Wright, J , Martin, NG , Montgomery, GW , Burrows, Kimberley , Moffitt, TE , Poulton, R , Esko, T , Milani, L , Metspalu, A , Perry, JRB , Ong, KK , Wareham, NJ , Matullo, G , Sacerdote, C , Suderman, Matthew , Panico, S , Caspi, A , Arseneault, L , Gagnon, F , Ollikainen, M , Kaprio, J , Felix, JF , Rivadeneira, F , Tiemeier, H , van IJzendoorn, MH
- Resource Type: journal article
- Date: 2021
The trans-ancestral genomic architecture of glycemic traits
- Creator: Chen, Ji , Spracklen, Cassandra N. , Marenne, Gaëlle , Varshney, Arushi , Corbin, Laura J. , Luan, Jian'an , Willems, Sara M. , Wu, Ying , Zhang, Xiaoshuai , Horikoshi, Momoko , Boutin, Thibaud S. , Mägi, Reedik , Waage, Johannes , Li-Gao, Ruifang , Chan, Kei Hang Katie , Yao, Jie , Anasanti, Mila D. , Chu, Audrey Y. , Claringbould, Annique , Heikkinen, Jani , Wang, Carol A. , Pennell, Craig E.
- Resource Type: journal article
- Date: 2021
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
- Creator: Fachal, Laura , Aschard, Hugues , Soucy, Penny , Scott, Rodney J. , Lemaçon, Audrey , Lush, Michael , Tyrer, Jonathan P. , Ghoussaini, Maya , Marjaneh, Mahdi Moradi , Jiang, Xia , Agata, Simona , Aittomäki, Kristiina , Alonso, M. Rosario , Beesley, Jonathon , Andrulis, Irene L. , Anton-Culver, H , Antonenkova, NN , Arason, A , Arndt, V , Aronson, KJ , Arun, BK , Auber, B , Auer, PL , Azzollini, J , Barnes, Daniel R. , Balmaña, J , Barkardottir, RB , Barrowdale, D , Beeghly-Fadiel, A , Benitez, J , Bermisheva, M , Bialkowska, K , Blanco, AM , Blomqvist, C , Blot, W , Allen, Jamie , Bogdanova, NV , Bojesen, SE , Bolla, MK , Bonanni, B , Borg, A , Bosse, K , Brauch, H , Brenner, H , Briceno, I , Brock, IW , Kar, Siddhartha , Brooks-Wilson, A , Brüning, T , Burwinkel, B , Buys, SS , Cai, Q , Caldés, T , Caligo, MA , Camp, NJ , Campbell, I , Canzian, F , Pooley, Karen A. , Carroll, JS , Carter, BD , Castelao, JE , Chiquette, J , Christiansen, H , Chung, WK , Claes, KBM , Clarke, CL , Mari, V , Berthet, P , Dennis, Joe , Castera, L , Vaur, D , Lallaoui, H , Bignon, YJ , Uhrhammer, N , Bonadona, V , Lasset, C , Révillion, F , Vennin, P , Muller, D , Michailidou, Kyriaki , Gomes, DM , Ingster, O , Coupier, I , Pujol, P , Collonge-Rame, MA , Mortemousque, I , Bera, O , Rose, M , Baurand, A , Bertolone, G , Turman, Constance , Faivre, L , Dreyfus, H , Leroux, D , Venat-Bouvet, L , Bézieau, S , Delnatte, C , Chiesa, J , Gilbert-Dussardier, B , Gesta, P , Prieur, FP
- Resource Type: journal article
- Date: 2020
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
- Creator: Huckins, Laura M. , Buccola, NG , Buckner, RL , Byerley, W , Cahn, W , Cai, G , Campion, D , Cantor, RM , Carr, VJ , Carrera, N , Catts, SV , Chambert, KD , Chan, RCK , Chen, RYL , Chen, EYH , Cheng, W , Cheung, EFC , Chong, SA , Cloninger, CR , Cohen, D , Cohen, N , Cormican, P , Craddock, N , Crowley, JJ , Curtis, D , Davidson, M , Davis, KL , Degenhardt, F , Del Favero, J , Demontis, D , Dikeos, D , Dinan, T , Djurovic, S , Donohoe, G , Drapeau, E , Duan, J , Dudbridge, F , Durmishi, N , Eichhammer, P , Eriksson, J , Dobbyn, Amanda , Boocock, James , Roussos, Panos , Fromer, Menachem , Kramer, Robin , Domenici, Enrico , Gamazon, Eric R. , Purcell, Shaun , Johnson, Jessica S. , Shah, Hardik R. , Klein, Lambertus L. , Ruderfer, Douglas M. , Henskens, Frans A. , Loughland, Carmel M. , Schall, Ulrich , Michie, Patricia T. , Scott, Rodney J. , Gur, RE , Hahn, CG , Schadt, E , Lewis, DA , Haroutunian, V , Hoffman, Gabriel , Peters, MA , Lipska, BK , Buxbaum, JD , Hirai, K , Perumal, TM , Essioux, L , Ripke, S , Neale, BM , Corvin, A , Walters, JTR , Wang, Weiqing , Farh, KH , Holmans, PA , Lee, P , Bulik-Sullivan, B , Collier, DA , Huang, H , Pers, TH , Agartz, I , Agerbo, E , Albus, M , Pardiñas, Antonio F. , Alexander, M , Amin, F , Bacanu, SA , Begemann, M , Belliveau, RA , Bene, J , Henskens, FA , Loughland, CM , Michie, PT , Schall, U , Rajagopal, Veera M. , Scott, RJ , Als, Thomas D. , Nguyen, Hoang T. , Girdhar, Kiran
- Resource Type: journal article
- Date: 2019
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
- Creator: Karlsson Linnér, Richard , Kalnapenkis, A , Kasela, S , Kettunen, J , Kim, Y , Kirsten, H , Kovacs, P , Krohn, K , Kronberg-Guzman, J , Kukushkina, V , Kutalik, Z , Lee, B , Lehtimäki, T , Loeffler, M , Marigorta, UM , Metspalu, A , Milani, L , Montgomery, GW , Müller-Nurasyid, M , Nauck, M , Penninx, B , Perola, M , Biroli, Poetro , Nivard, Michel G. , Okbay, Aysu , Rietveld, Cornelius A. , Timshel, Pascal N. , Trzaskowski, Maciej , de Vlaming, Ronald , Zünd, Christian L. , Bao, Yanchun , Buzdugan, Laura , Caplin, Ann H. , Kong, Edward , Chen, Chia-Yen , Eibich, P , Fontanillas, P , Gonzalez, JR , Joshi, PK , Karhunen, V , Kleinman, A , Levin, RZ , Lill, CM , Meddens, GA , Meddens, S. Fleur W. , Muntané, G , Sanchez-Roige, S , Rooij, FJV , Taskesen, E , Wu, Y , Zhang, F , Agee, M , Alipanahi, B , Bell, RK , Bryc, K , Wedow, Robbee , Elson, SL , Furlotte, NA , Huber, KE , Litterman, NK , McCreight, JC , McIntyre, MH , Mountain, JL , Northover, CAM , Pitts, SJ , Sathirapongsasuti, JF , Fontana, Mark Alan , Sazonova, OV , Shelton, JF , Shringarpure, S , Tian, C , Tung, JY , Vacic, V , Wilson, CH , Agbessi, M , Ahsan, H , Alves, I , Lebreton, Maël , Andiappan, A , Awadalla, P , Battle, A , Beutner, F , Jan Bonder, M , Boomsma, DI , Christiansen, M , Claringbould, A , Deelen, P , Esko, T , Tino, Stephen P. , Favé, MJ , Franke, L , Frayling, T , Gharib, SA , Gibson, G , Oldmeadow, Christopher , Holliday, Elizabeth G. , Scott, Rodney J. , Attia, John R. , Abdellaoui, Abdel , Hammerschlag, Anke R.
- Resource Type: journal article
- Date: 2019
Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton
- Creator: Hu, Yan , Chen, Jiedan , Baruch, Kobi , Fang, David , Liu, Xia , Ruan, Yong-ling , Rahman, Mehboob-ur , Han, Jinlei , Wang, Kai , Wang, Qiong , Wu, Huaitong , Mei, Gaofu , Fang, Lei , Zang, Y , Han, Z , Xu, C , Shen, W , Yang, D , Si, Z , Dai, F , Zou, L , Huang, F , Bai, Y , Zhang, Zhiyuan , Zhang, Y , Brodt, A , Ben-Hamo, H , Zhu, X , Zhou, B , Guan, X , Zhu, S , Chen, X , Zhang, T , Ma, Wei , Niu, Yongchao , Ju, Longzhen , Deng, Jieqiong , Zhao, Ting , Lian, Jinmin
- Resource Type: journal article
- Date: 2019
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
- Creator: Warrington, Nicole M. , Beaumont, Robin N. , Wood, Andrew R. , Pennell, Craig E. , Mahajan, Anubha , Tyrrell, Jessica , Robertson, Neil R. , Rayner, N. William , Qiao, Zhen , Moen, Gunn-Helen , Vaudel, Marc , Marsit, Carmen J. , Chen, Jia , Horikoshi, Momoko , Nodzenski, Michael , Schnurr, TM , Zafarmand, MH , Bradfield, JP , Grarup, N , Kooijman, MN , Li-Gao, R , Geller, F , Ahluwalia, TS , Paternoster, L , Day, Felix R. , Rueedi, R , Huikari, V , Hottenga, JJ , Lyytikäinen, LP , Cavadino, A , Metrustry, S , Cousminer, DL , Wu, Y , Thiering, E , Wang, Carol A. , Helgeland, Øyvind , Have, CT , Vilor-Tejedor, N , Joshi, PK , Painter, JN , Ntalla, I , Myhre, R , Pitkänen, N , van Leeuwen, EM , Joro, R , Lagou, V , Laurin, Charles , Richmond, RC , Espinosa, A , Barton, SJ , Inskip, HM , Holloway, JW , Santa-Marina, L , Estivill, X , Ang, W , Marsh, JA , Reichetzeder, C , Bacelis, Jonas , Marullo, L , Hocher, B , Lunetta, KL , Murabito, JM , Relton, CL , Kogevinas, M , Chatzi, L , Allard, C , Bouchard, L , Hivert, MF , Peng, Shouneng , Zhang, G , Muglia, LJ , Heikkinen, J , Morgen, CS , van Kampen, AHC , van Schaik, BDC , Mentch, FD , Langenberg, C , Luan, J , Scott, RA , Hao, Ke , Zhao, JH , Hemani, G , Ring, SM , Bennett, AJ , Gaulton, KJ , Fernandez-Tajes, J , van Zuydam, NR , Medina-Gomez, C , de Haan, HG , Rosendaal, FR , Feenstra, Bjarke , Kutalik, Z , Marques-Vidal, P , Das, S , Willemsen, G , Mbarek, H , Müller-Nurasyid, M , Standl, M , Appel, EVR , Fonvig, CE , Trier, C
- Resource Type: journal article
- Date: 2019
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
- Creator: Justice, Anne E. , Karaderi, Tugce , Highland, Heather M. , Young, Kristin L. , Graff, Mariaelisa , Lu, Yingchang , Turcot, Valérie , Auer, Paul L. , Fine, Rebeccaa S. , Guo, Xiuqing , Schurmann, Claudia , Lempradl, Adelheid , Marouli, Eirini , Mahajan, Anubha , Winkler, Thomas W. , Locke, Adam E. , Medina-Gomez, Carolina , Esko, Tõnu , Vedantam, Sailaja , Giri, Ayush , Pennell, Craig E. , Wang, Carol A. , Lo, Ken Sin , Alfred, T , Mudgal, P , Ng, MCY , Heard-Costa, NL , Feitosa, MF , Manning, AK , Willems, SM , Sivapalaratnam, S , Abecasis, G , Alam, DS , Allison, M , Amouyel, P , Arzumanyan, Z , Balkau, B , Bastarache, L , Bergmann, S , Bielak, LF , Blüher, M , Boehnke, M , Boeing, H , Boerwinkle, E , Böger, CA , Bork-Jensen, J , Bottinger, EP , Bowden, DW , Brandslund, I , Broer, L , Burt, AA , Butterworth, AS , Caulfield, MJ , Cesana, G , Chambers, JC , Chasman, DI , Chen, YDI , Chowdhury, R , Christensen, C , Chu, AY , Collins, FS , Cook, JP , Cox, AJ , Crosslin, DS , Danesh, J , de Bakker, PIW , Denus, SD , Mutsert, RD , Dedoussis, G , Demerath, EW , Dennis, JG , Denny, JC , Angelantonio, ED , Dörr, M , Drenos, F , Dubé, MP , Dunning, AM , Easton, DF , Elliott, P , Evangelou, E , Farmaki, AE , Feng, S , Ferrannini, E , Ferrieres, J , Florez, JC , Fornage, M , Fox, CS , Franks, PW , Friedrich, N , Gan, W , Gandin, I , Gasparini, P , Giedraitis, V , Girotto, G , Gorski, M , Grallert, H , Grarup, N , Grove, ML , Gustafsson, S , Haessler, J , Hansen, T , Hattersley, AT
- Resource Type: journal article
- Date: 2019
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
- Creator: Giri, Ayush , Hellwege, Jacklyn N. , Keaton, Jacob M. , Park, Jihwan , Qiu, Chengxiang , Warren, Helen R. , Torstenson, Eric S. , Kovesdy, Csaba P. , Sun, Yan V. , Wilson, Otis D. , Robinson-Cohen, Cassianne , Roumie, Christianne L. , Chung, Cecilia P. , Birdwell, Kelly A. , Damrauer, Scott M. , DuVall, Scott L. , Klarin, Derek , Cho, Kelly , Wang, Yu , Evangelou, Evangelos , Attia, John , Oldmeadow, Christopher , Wei, WQ , Jarvelin, MR , Hennig, BJ , Timpson, NJ , Smith, JC , Xu, Y , Matheny, ME , Siew, EE , Lindgren, C , Herzig, KH , Dedoussis, G , Denny, JC , Psaty, BM , Howson, JMM , Munroe, PB , Newton-Cheh, C , Caulfield, MJ , Elliott, P , Gaziano, JM , Concato, J , Wilson, PWF , Tsao, PS , Velez Edwards, DR , Susztak, K , O¿Donnell, CJ , Hung, AM , Edwards, TL , Cabrera, Claudia P. , Wain, LV , Shrestha, R , Mautz, BS , Akwo, EA , Sargurupremraj, M , Debette, S , Boehnke, M , Scott, LJ , Luan, J , Zhao, JH , Willems, SM , Thériault, S , Shah, N , Almgren, P , Li-Gao, R , Verweij, N , Boutin, TS , Mangino, M , Ntalla, I , Feofanova, E , Surendran, P , Cook, JP , Karthikeyan, S , Lahrouchi, N , Liu, C , Sepúlveda, N , Richardson, TG , Kraja, A , Amouyel, P , Farrall, M , Poulter, NR , Laakso, M , Zeggini, E , Sever, P , Scott, RA , Langenberg, C , Wareham, NJ , Conen, D , Palmer, CNA , Chasman, DI , Ridker, PM , Melander, O , Mook-Kanamori, DO , van der Harst, P , Cucca, F , Schlessinger, D , Hayward, C , Spector, TD
- Resource Type: journal article
- Date: 2019
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
- Creator: Wu, Lang , Shi, Wei , Al-Ejeh, Fares , Rozali, Esdy , Wang, Qin , Dennis, Joe , Li, Bingshan , Zeng, Chenjie , Feng, Helian , Gusev, Alexander , Barfield, Richard T. , Andrulis, Irene L. , Long, Jirong , Scott, Rodney J. , Arndt, V , Aronson, KJ , Auer, PL , Barrdahl, M , Baynes, C , Beckmann, MW , Benitez, J , Bermisheva, M , Blomqvist, C , Guo, Xingyi , Bogdanova, NV , Bojesen, SE , Brauch, H , Brenner, H , Brinton, L , Broberg, P , Brucker, SY , Burwinkel, B , Caldés, T , Canzian, F , Michailidou, Kyriaki , Carter, BD , Castelao, JE , Chang-Claude, J , Chen, X , Cheng, TYD , Christiansen, H , Clarke, CL , Collée, M , Cornelissen, S , Couch, FJ , Beesley, Jonathan , Cox, D , Cox, A , Cross, SS , Cunningham, JM , Czene, K , Daly, MB , Devilee, P , Doheny, KF , Dörk, T , Dos-Santos-Silva, I , Bolla, Manjeet K. , Dumont, M , Dwek, M , Eccles, DM , Eilber, U , Eliassen, AH , Engel, C , Eriksson, M , Fachal, L , Fasching, PA , Figueroa, J , Shu, Xiao-Ou , Flesch-Janys, D , Fletcher, O , Flyger, H , Fritschi, L , Gabrielson, M , Lu, Yingchang , Cai, Qiuyin
- Resource Type: journal article
- Date: 2018
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
- Creator: Lee, James J. , Wedow, Robbee , Okbay, Aysu , Kong, Edward , Maghzian, Omeed , Zacher, Meghan , Nguyen-Viet, Tuan Anh , Bowers, Peter , Sidorenko, Julia , Karlsson Linnér, Richard , Fontana, Mark Alan , Kundu, Tushar , Lee, Chanwook , Li, Hui , Li, Ruoxi , Royer, Rebecca , Timshel, Pascal N. , Walters, Raymond K. , Willoughby, Emily A. , Yengo, Loïc , Agee, Michelle , Oldmeadow, Christopher , Holliday, Elizabeth G. , Scott, Rodney J. , Attia, John R.
- Resource Type: journal article
- Date: 2018